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Benfotiamine and Methyl B12 Vitamins for Neuropathy

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Benfotiamine and Methyl B12 Vitamins for Neuropathy

Jun 14, 2011 | By Laura Parr Laura Parr began her professional writing career in 2008 contributing to websites such as Travelbox, 1stop and Traveldojo. She now writes health and fitness-related articles. Parr earned a diploma of adult nursing from the University of Brighton, followed by a postgraduate certificate in public health from the University of Manchester.
B12 & Benfotiamine Vitamins
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B12 and benfotiamine vitamins are essential nutrients needed by your body. B12 is found in high quantities in beef liver and clams, as stated by the Office of Dietary Supplements, but it can also be found in other fish, meat and dairy products, as well as in fortified cereals. Benfotiamine is derived from thiamine and is thought to be beneficial in the treatment of diabetes and Alzheimer’s disease.

Vitamin B12

B12 is essential for the maintenance of red blood cells and nerve cells, and the production of DNA, according to the Mayo Clinic. Additionally, B vitamins, including B12, are important for mood regulation and other brain functions. Vitamin B12 deficiency has been linked to breast cancer in women, Alzheimer’s disease and cardiovascular disease, although there is, as of 2010, insufficient scientific evidence to support such claims. A 2009 article published in the Journal of the American Board of Family Medicine found that 22 percent of people with type 2 diabetes had a B12 deficiency.

Vitamin B12 Uses

B12 is stored in the body for years, so it is rare for individuals to become deficient. However, some people are unable to absorb B12 from the intestine, which can lead to pernicious anemia. A B12 supplement may be recommended by a health professional to treat a B12 deficiency.

To holistically treat any emotional issues arising from a B12 deficiency, you should eat a healthy diet that includes meat, fish or dairy products or fortified cereals. Speak to a health professional if you feel depressed or are considering taking B12 supplements.


Benfotiamine is a derivative of thiamine or vitamin B1. Benfotiamine is used in the treatment of diabetic neuropathy, and, as of 2010, studies are underway to determine other uses for the vitamin. Benfotiamine is known to be safe to take as a supplement, and is not linked to any serious side effects, according to Brain, a Journal of Neurology, an Oxford Journal publication.

Benfotiamin Uses

In 2006, scientists at the American Diabetes Association found benfotiamine to be beneficial in preventing blood vessel degeneration in patients with type 2 diabetes, while a 2010 study published in Diabetologia found that thiamine and benfotiamine may actually reverse some of the symptoms of a diabetes-like disease in rats.

In 2010, scientists reported in Brain, a Journal of Neurology, that benfotiamine may be useful for the clinical treatment of Alzheimer’s disease after they studied mice with a similar condition.

Use of Both B12 and Benfotiamine

Further research is needed on both the clinical implications of vitamin B12 deficiency in diabetics and the use of benfotiamine in treating diabetes. However, with proper research and application, they may, at some point, be both used as diabetes treatments.


Article reviewed by SPEstes Last updated on: Jun 14, 2011

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